Twilight fans have already started to queue at Comic-Con ahead of the Breaking Dawn - Part 2 on July 12.
Despite warnings from the event organisers fans have already started to arrive to ensure they get into the fan event.
Kristen Stewart, Robert Pattinson, Taylor Lautner, Peter Facinelli, Elizabeth Reaser, Kellan Lutz, Nikki Reed, Jackson Rathbone, Ashley Greene and Mackenzie Foy will be panelists at the movie franchise's final year at Comic-Con.
It is expected that some new footage of the film will be released during the session.
Organisers have taken to twitter to ask fans not to head to the venue before the Comic-Con launch on Wednesday.
The message said: "Please do not line up for Hall H, set-up is not complete. Read the complete line-up guidelines #SDCC #twilight."
Thousands of fans are expected to try and get in the see the panel, but new rules have been issued to fans who arrive early to get a place in line.
The will not be allowed to camp, chairs must be a "relatively normal size", and no facilities or services will be available in the park.
This is a change from previous years when fans often arrived in advance and camped out for days.
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